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Image Search Results
Journal: Frontiers in Systems Neuroscience
Article Title: Distinguishing cognitive state with multifractal complexity of hippocampal interspike interval sequences
doi: 10.3389/fnsys.2015.00130
Figure Lengend Snippet: Multifractal detrended fluctuation analysis . An illustration of the MFDFA method was created using one CA1 neuron recorded on two different days: one vehicle condition (blue) and one tetrahydrocannbinol (THC) condition (green). (A) The interspike interval sequence (ISI) of each neuron is shown for the first 2000 ISIs. Five seconds were subtracted from the entire THC ISI sequence for illustration purposes only. (B) The fluctuation function F is shown at scale 16 ( s = 16) for four different q-order statistical moments. Negative q-order statistical moments amplify small fluctuations, while positive moments amplify large fluctuations. Inset: F 2 ( v, s ) is the root mean-squared residual between the fit y v (black) of one segment s from the walk-like time series Y (blue). (C) The changes in variability across scales are indicated by variable slopes at different qth powers (integer q-values from −3 to 3). The q-order Hurst exponent H(q) is the slope of each regression line. Blue lines are from the vehicle recording and green lines are from the THC recording. Dots indicate individual values from each scale (19 scales ranging from 16 to 256). (D) Multifractal complexity is visualized with the multifractal singularity spectrum. The Hurst exponent is closely related to the h -value at the apex of the singularity spectrum (black data points). The width is obtained by subtracting h -values at each end of the spectrum (independent of D(h) values) indicated by the black arrow. The singularity spectrum for the vehicle condition is wider than the THC condition, indicating THC decreases multifractality.
Article Snippet: All analyses were performed in
Techniques: Sequencing